Tadalafil, the active ingredient in 24-hour Cialis, inhibits phosphodiesterase-5 (PDE5), an enzyme that breaks down cyclic guanosine monophosphate (cGMP). Higher cGMP levels relax blood vessels, improving blood flow to the penis, facilitating erections.
Clinical trials demonstrate Tadalafil’s ability to produce erections suitable for sexual intercourse for up to 36 hours after a single dose. This prolonged effect stems from Tadalafil’s longer half-life compared to other PDE5 inhibitors. However, an erection won’t occur without sexual stimulation.
Regarding safety, common side effects include headache, flushing, nasal congestion, and indigestion, typically mild and transient. Rare but serious side effects include sudden vision loss or hearing loss. Consult your doctor immediately if you experience these.
Tadalafil interacts with certain medications, particularly nitrates used to treat angina. This combination can cause a dangerous drop in blood pressure. Always disclose all medications you are taking to your doctor before starting Tadalafil.
Individuals with certain pre-existing conditions, such as heart disease, stroke, or low blood pressure, should discuss the risks and benefits with their physician before using Tadalafil. Regular check-ups are advisable to monitor for any adverse effects.
Remember, this information does not substitute professional medical advice. Always consult a healthcare provider for personalized guidance and to determine if 24-hour Cialis is right for you.